Glutathione Depleting Pro Oxidant as a Selective Anticancer Therapeutic Agent ACS Omega Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression: Cancer Cell Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega