Does a B12 shot change urine color to pinkish? Riboflavin & Yellow Urine: Are You Taking The Right Multivitamin? ReNue Rx Vitamin B12 shots are an excellent way to gain energy quickly while positively impacting your overall health. B vitamins are essential for the body to function properly, because they assist with boosting Figure 3 from Quantification of chromatographic effects of vitamin B supplementation in urine and implications for hydration assessment. Semantic Scholar