The role of NAD+ metabolism and its modulation of mitochondria in aging and disease npj Metabolic Health and Disease NAD with Glutathione: Powerful Duo for Detox, Energy, and Anti Aging Shed Glutathione vs. NAD+: How they work together for stronger cellular health Glutathione (GSH) and NAD are both critical for cellular health, energy, and repair. Yet, they function very differently in the body. The question I'm often asked is, "Which one do I need